Sunday, September 25, 2011

Mouse Behavioral Testing: How to use mice in behavioral neuroscience

Mouse Behavioral Testing: How to use mice in behavioral neuroscience

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Product Description

This book presents the essentials of behavioral test methodology needed for effective study planning and high quality behavioral data collection on laboratory mice. The broad scope of behavioral testing in relation to the neurosciences is discussed, as are the fine details of various� test situations. Mistakes made in past research are scrutinized and lessons are drawn about how to avoid them in future work. Diverse factors that can influence the results of behavioral experiments are discussed, ranging from the specific parameters employed in a test to the laboratory environment outside the test situation itself. Throughout the book, emphasis is placed on special issues that arise when testing genetically different mice, including inbred strains and mice with targeted mutations. This knowledge will assist an investigator who lacks formal training in behavioral psychology to build a behavioral testing lab and insure that its output meets current standards of good practice in behavioral neuroscience research.

The book will be a convenient manual of procedures for daily use in studies of mouse behavior. It will be of interest even to experienced behavioural researchers, but of particular value to scientists just beginning work with mice, including undergraduate and graduate students as well as postdoctoral investigators who want to collect phenotypic data with knockout and other genetically defined mice. Constructed from materials used in a long running course on Advanced Animal Behavior at University of North Carolina-Greensboro, the book is an ideal text for a course on behavioral testing.



  • A guide to running a behavioral testing lab, including the many aspects of mouse research beyond the confines of the specific test
  • Diagrams and photographs are shown for many kinds of apparatus and test situations with sufficient details such as dimensions to enable building of replicas
  • Provides step-by-step instructions on planning and executing behavioral experiments in order to run them successfully
  • A companion website will provide access to statistical utilities in Excel and test protocols, examples of real documents used for published studies, and video clips of the mice behaviors resulting from various tests
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Mouse Behavioral Testing: How to use mice in behavioral neuroscience Review

This is a must-have book. It's very comprehensive and should be obligatory reading for anybody doing behavioral research with mice. In addition, Wahlsten's dry humor makes this a fun read, even the "dryer" chapters: I found myself cracking up regularly while reading his statistics chapter... And his chapter on research ethics should be obligatory reading for everybody involved in animal experimentation, not just mouse behaviorists.

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Saturday, September 24, 2011

Pharmacology: Principles and Practice

Pharmacology: Principles and Practice

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This unique and much needed textbook meets the rapidly emerging needs of programs training pharmacologic scientists seeking careers in basic research and drug discovery rather than such applied fields as pharmacy and medicine. While the market is crowded with many clinical and therapeutic pharmacology textbooks, the field of pharmacology is booming with the prospects of discovering new drugs, and virtually no extant textbook meets this need at the student level. The market is so bereft of such approaches that many pharmaceutical companies will adopt Hacker, et al. to help train new drug researchers.

The boom in pharmacology is driven by the recent decryption of the human genome and enormous progress in controlling genes and synthesizing proteins, making new and even custom drug design possible. This book makes use of these discoveries in presenting its topics, moving logically from drug receptors to the target molecules drug researchers seek, covering such modern topics along the way as side effects, drug resistance, Pharmacogenomics, and even nutriceuticals, one in a string of culminating chapters on the drug discovery process.

*Uses individual drugs to explain molecular actions
*Full color art program explains molecular and chemical concepts graphically
*Logical structure reflecting the current state of pharmacology and translational research
*Covers such intricacies as drug resistance and cell death
*Consistent format across chapters and pedagogical strategies make this textbook a superior learning tool

Pharmacology: Principles and Practice Review

This book is great if you ever work in the field/ have to deal with in an extreme detailed level of Pharmacokinetics. If you aren't dealing with PK things on an extremely detailed level do not get this book. I mean it is good for other things, but not much else.

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Friday, September 23, 2011

Electromyography in Clinical Practice: A Case Study Approach

Electromyography in Clinical Practice: A Case Study Approach

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The only case-based guide to electromyography-back in a fully revised and updated New Edition! This practical resource examines how to approach, diagnose, and manage the most commonly encoun-tered disorders in the EMG laboratory. Based on actual cases, it correlates patient history, physical exam, EMG findings, relevant anatomy, treatment, and follow-up to help readers sharpen their clinical problem-solving skills. New cases have been added, and every case includes the latest advances in knowledge and technique.
  • Features study questions, answers, and clinical discussions of how experts manage cases to help readers work through the problems presented.
  • Summarizes the results of nerve conduction studies and EMG data with standardized tables.
  • Includes more than 200 relevant imaging studies and anatomic figures.
  • Makes information easy to find with a uniform chapter organization.
  • Offers a consistent approach to electromyography based on Dr. Katirji's broad knowledge and clinical experience.
  • 7 new case studies, including Hereditary Neuropathy with Liability to Pressure Palsy, Ischemic Monomelic Neuropathy, and Myotonic Dystrophy.
  • Three new chapters on Nerve Conduction Studies, Needle EMG Examination, and Specialized Procedures.
  • Many new and revised figures that clarify complex information.

Electromyography in Clinical Practice: A Case Study Approach Review

I studied this book many times (resident, fellow, before exams), and every time I found myself learning from it more and more.
It is about 300 pages, with 25 cases. The first 16 cases deal with common entrapment neuropathies, radiculopathies, etc in upper and lower extremities (8 cases each). The last nine cases are oriented for generalized diseases such as Myasthenia, AIDP, botulism, etc. Each case starts with history/exam followed by few questions. The next 2-3 pages are the NCS/ENG findings. The next 5-15 pages (varies between cases) are rich with very informative discussion about the electrophysiological findings, anatomy with pictures and charts, clinical with few tables, then a lengthy electrophysiological explanations about the particular case and its differential diagnosis, with many tables( key EMG muscles, LEMS versus MG). The case ends with a follow up.
As I said above, I keep learning from this book, and I do not hesitate to recommend it.

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Thursday, September 22, 2011

Fundamental Food Microbiology, Fourth Edition

Fundamental Food Microbiology, Fourth Edition

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In the last few years the discipline of food microbiology has undergone a radical change. Fundamental Food Microbiology, Second Edition reflects this change and meets the need for a better understanding of food microbiology. Revised and updated, this new edition of a bestseller includes current developments in different aspects of food microbiology.

The book is divided into seven sections arranged in a logical fashion to depict various areas of food microbiology. These subjects include: the history of food microbiology and microorganisms important in food; microbial growth and metabolism in food; beneficial uses of microorganisms; spoilage of foods by microorganisms and their enzymes; foodborn, pathogens associated with intoxication, infections, and toxicoinfections; control of undesirable microorganisms; and nonthermal methods and combination methods in food preservation. Tables, figures, and data are presented to provide better understanding, and a list of selected references and suggested questions have been included at the end of each chapter.

Intended for use as a text for undergraduate food microbiology courses, this book also provides basic and applied information in many other areas, and can be used as a text in courses dealing with microbiology, public health, nutrition and dietetics, veterinary science, and medical science. This is a valuable reference for anyone associated with the microbiological aspects of food.

Fundamental Food Microbiology, Fourth Edition Review

In my opinion this book is great. It covers all the basic stuff that you need to know about food microbiology. It is not in depth, but covers just all the things that you need to know. I like it a lot.

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Wednesday, September 21, 2011

Intelligent Data Analysis: An Introduction

Intelligent Data Analysis: An Introduction

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This monograph is a detailed introductory presentation of the key classes of intelligent data analysis methods. The twelve coherently written chapters by leading experts provide complete coverage of the core issues. The first half of the book is devoted to the discussion of classical statistical issues, ranging from the basic concepts of probability, through general notions of inference, to advanced multivariate and time series methods, as well as a detailed discussion of the increasingly important Bayesian approaches and Support Vector Machines. The following chapters then concentrate on the area of machine learning and artificial intelligence and provide introductions into the topics of rule induction methods, neural networks, fuzzy logic, and stochastic search methods. The book concludes with a chapter on Visualization and a higher-level overview of the IDA processes, which illustrates the breadth of application of the presented ideas.

Intelligent Data Analysis: An Introduction Review

This is a book by Springer Verlag that came out if 1999. This book introduces a lot of useful statistical tools and has chapters written by statisticians and computer scientists. The editors also contribute. They emphasize useful tools and computer tools. It includes material from the artificial intelligence literature including fuzzy set logic, genetic algorithms and expert systems. There is some discussion of data mining, Bayesian methods and neural networks.

Chapters are written on an elementary level for students and pratictioners of modern data analysis techniques. Written mainly as a text but expanded to cover topics of interest to researchers in statistics and computer science by subject matter experts. The last chapter on Systems and Applications by Xiaohui Liu includes coverage of data quality. Among the references on data quality and outlier detection is the book edited by Wright "Statistical Methods and the Improvement of Data Quality". That book was a collection of papers from a conference held in Oak Ridge Tennessee in 1982. That volume was published by Academic Press in 1983. It is not often sighted in the statistical literature but it did contain a number of interesting papers. I contributed a chapter on influence function methods for outlier detection to the Academic Press book.

Hand has written many books on statistics and especially some excellent texts on classification and pattern recognition. His recent work on data mining was published in 1999 by MIT press, a volume he coauthored with Mannila and Smyth. it is one of teh few data mining texts that is highly regarded by the statistical community. Much of that work in referenced in this book particularly in Chapter 1, the overview chapter on intellegent data analysis that Hand wrote himself.

Resampling methods, generalized linear models, Bayesian methods, time series, multivariate analysis, random effects models and entropy are all covered with nice elementary introductions.

This is a great reference source with over 440 articles and books in the list of references.

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Tuesday, September 20, 2011

Presidents and Civil Liberties from Wilson to Obama

Presidents and Civil Liberties from Wilson to Obama

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This book is a history of the civil liberties records of American presidents from Woodrow Wilson to Barack Obama. It examines the full range of civil liberties issues: First Amendment rights of freedom of speech, press and assembly; due process; equal protection, including racial justice, women's rights, and lesbian and gay rights; privacy rights, including reproductive freedom; and national security issues. The book argues that presidents have not protected or advanced civil liberties, and that several have perpetrated some of the worst violations. Some Democratic presidents (Wilson and Roosevelt), moreover, have violated civil liberties as badly as some Republican presidents (Nixon and Bush). This is the first book to examine the full civil liberties records of each president (thus, placing a president's record on civil rights with his record on national security issues), and also to compare the performance on particular issues of all the presidents covered.

Presidents and Civil Liberties from Wilson to Obama Review

Liberals have their list of great presidents and conservatives, theirs, but no one on any position in the political spectrum could likwly anticipate some of the findings of this book. Certainly I didn't. Wilson, who I thought one of the great Democratic Party progressives, was in fact arguably more repressive than any Republican President and wanted only to "crush" those who disagreed with his leading America into WW I. We all know about Harding, or think we do, until we find that he was the first President and the last until Truman, to advocate for full political equality for African-Americans, going so far as to beard the lions of segregation in their own Birmingham Alabama den, with a civil rights speech that certainly ranks among the most courageous ever given by an American president. And on it goes, our heroes are found to have blemishes and our villains have unexpected laurels when it comes to civil rights and civil liberties. The generalization one can make is that when we elect a president, be our choice conservative or liberal, we won't know until later how they actually feel about our bill of rights protections...and this book shows that generally the record has not been good. Well-written, concise histories of each presidency starting with Wilson to the present are given and the 500+ pages of fine print, well annotated, is a joy to read either seriatum or simply dipping into various president's administrations. I would recommend, with this book, a companion piece of reading: Political Repression in Modern America from 1870 to the Present, by Robert J Goldstein, a reworking and amended version of a doctoral dissertation. Goldstein's book further illuminates some of the incidents you will find interesting in Samuel Walker's excellent book.

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