Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology

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THEORY AND PRACTICE OF MODELING AND SIMULATING HUMAN PHYSIOLOGY

Written by a coinventor of the Human Patient Simulator (HPS) and past president of the Society in Europe for Simulation Applied to Medicine (SESAM), Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology is a compact and consistent introduction to this expanding field. The book divides the modeling and simulation process into five manageable steps--requirements, conceptual models, mathematical models, software implementation, and simulation results and validation.

A framework and a basic set of deterministic, continuous-time models for the cardiorespiratory system are provided. This timely resource also addresses advanced topics, including sensitivity analysis and setting model requirements as part of an encompassing simulation and simulator design. Practical examples provide you with the skills to evaluate and adapt existing physiologic models or create new ones for specific applications.

Coverage includes:

• Signals and systems
• Model requirements
• Conceptual models
• Mathematical models
• Software implementation
• Simulation results and model validation
• Cardiorespiratory system model
• Circulation
• Respiration
• Physiologic control
• Sensitivity analysis of a cardiovascular model
• Design of model-driven acute care training simulators

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Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology Review

If you are interested in knowing how physiologic simulation design and development works, but have been scared off by other texts, this book is for you. Some modeling books are heavy on the math and quickly lose all but the most mathematically inclined reader. Some modeling books concentrate almost exclusively on the theory because they are written by academicians who lack practical application experience. This book is different! It is written by a pioneer in human patient simulation modeling as one of the developers of the most advanced human patient simulator on the market, that does not have an equal nearly 20 years after its development. Dr. van Meurs teaches the systems engineering approach to model development, emphasizing that simulation for education should be driven by learning requirements, not the other way around. This book is well done because it gives the entire scope and breadth of model development without getting lost in the weeds. Plenty of references are given for those who desire to delve deeper. The book is written in a conversational style with plenty of white space and many illustrations to make the read easy on the eyes and accessible to a broad spectrum of readers. Highly recommend.

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